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BCP Partnering Portal / Crown Bioscience Inc

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Crown Bioscience Inc
Crown Bioscience Inc

Crown Bioscience Inc

Company Type:
Business Address:
16550 West Bernardo Drive
Building 5, Suite 525
San Diego
United States of America
+1 603 686-9330
+1 858 622 2900
Pharma & Biotech
Scientific Services
Product Type:
Software & Informatics
Products, Services & Applications:
Genomics & Epigenetics
Drug Discovery Services
Drug Development Services
Contract Research Organisation (CRO)
About Us:

CrownBio is a Cutting-Edge Translational Technology Company Making Precision Medicine a Reality

CrownBio brings clarity to drug discovery around the world by helping biopharmaceutical companies solve some of today's most pressing challenges in oncology and inflammation.

Our premier Translational Platforms for cancer and inflammation help our clients accelerate their new drug development programs. CrownBio develops world-leading preclinical efficacy models and provides both in vitro and in vivo testing services. We are a global company with facilities across the world, including in the United States, United Kingdom, Netherlands, China, and Taiwan.
We Help our Clients Accelerate Drug Discovery, Gain Insight and De-Risk Ushering Candidates into the Clinic

As a comprehensive solution provider, CrownBio helps reveal the best clinical possibilities with our proprietary HuPrime®, HuKemia®, HuBase™, HuMark™, HuTrial™, and HuSignature™ platforms enabling the rapid translation of a lead compound into a successful clinical candidate. CrownBio's cutting-edge, proprietary, Translational Technology Platforms provide robust and scientifically sound end-to-end solutions for preclinical drug development.
The Premier Translational Platforms for Advanced Drug Discovery

From large-scale in vitro and in vivo efficacy studies of drug candidates, to running surrogate trials in tandem with human clinical trials, CrownBio's well-characterized Translational Platforms deliver comprehensive and catered solutions for biopharmaceutical companies. By providing the data needed to inform and accelerate oncology and inflammation therapeutic development, CrownBio helps clients make smarter decisions about their drug candidates.

With more experience than anyone in the industry, CrownBio's global resources help customers answer the most challenging questions about human biology.

CrownBio's portfolio of cutting-edge technologies includes the world's largest commercial collection of validated patient-derived xenograft (PDX) models. At CrownBio we are seeking to recapitulate the diversity and complexity of human cancer biology in the laboratory.
Our Translational Technology Platforms are helping our clients make precision medicine a reality.

More Info About Our Products:


Cell Line Derived Xenograft
HSC and PBMC Humanized
Human Target Knock-In ( HuGEMMTM )
Patient-Derived Xenograft ( HuPrimeTM )
Tumor Homograft ( MuPrimeTM )


In Vivo Models

Inflammatory Bowel Disease (IBD)
Rheumatoid Arthritis (RA)
Rodent Models of Diabetes

Biomarker Services

Flow Cytometry Platform
Histology and Digital Pathology Platform


In Vivo Services

Breast Cancer Preclinical Models
Cell Line Derived Xenograft Models
Cell Line and Model Authentication
Custom Tumor Model Development
Immuno-Oncology Model
Orthotopic and Bioluminescent Models
Patient-Derived Xenograft Models (HuPrime/HuKemia)
Prostate Cancer Preclinical Model
Radiation Therapy
Syngeneic Tumor Models

In Vitro Services

Cell Based Screening
Cell Line and Model Authentication
Cell Line Panels
Flow Cytometry Platform
OmniScreen Cell Based Screening Service
PDX-Derived Cell Lines


Cell Line and Model Authentication
Organoid and Immune Cell Co-Culture

Ex Vivo Services

3D Assays
Tumor Microarrays

High Content Imaging


CAR-T Cell Therapy Models
Humanized Models
Hematopoietic Stem Cell (HSC)-PDX
Human Target Knock-In Models
Murine Immunity Model and Services
Tumor Homograft
Syngeneic tumor
Mouse I/O RNA-Seq Panel


Biomarker Discovery and CDx

Biomarkers of Response (HuMark)
Mouse Clinical Trials (HuTrial)
Signatures of Response (HuSignature)

Biomarker Assay Services

Clinical Chemistry and Biomarkers
Cytokine and Chemokine Profiling
Flow Cytometry
Genomics Services
Mouse I/O RNA-Seq Panel
Histology and Digital Pathology
Rare Cell Analysis



Pharmacology and Bioanalytical Services

DMPK Services
Rodent Immuno-Safety Models
Rodent Safety Pharmacology
Structural Biology
Target Validation

Oncology Databases


Parent Company:
JSR Corp Japan (Japan)
Local Offices:
Crown Bioscience Netherlands BV (The Netherlands)
Crown Bioscience UK (United Kingdom)
Sister Companies:
Medical & Biological Labs (MBL) (Japan)
MBL International Corp (MBLI) (United States of America)
JSR Life Sciences / MBLI (Belgium)
JSR Micro Inc (United States of America)
Official Distributors:
Atlantis Bioscience Pte Ltd (Singapore)
On Target Co Ltd (Japan)
The Jackson Laboratory (United States of America)