INITIO Cell Ltd

Initio Cell is a company that develops and provides organ-on-chip devices and assays for drug discovery and diagnostics. The company's core business involves creating microfluidic devices that mimic the in vivo conditions of human organs, allowing for more accurate and relevant testing of drugs and cellular interactions. Initio Cell's products include various types of organ-on-chip devices, such as the DDI-Chip, IC-Chip, and IC-Chip Organoid, which can be used to study cell-cell interactions, invasion, chemotaxis, and other cellular behaviors. The company also offers contract research organization (CRO) services, including toxicity assessment, efficacy testing, and cell-cell interaction studies, using its organ-on-chip technology. Additionally, Initio Cell provides AI-based image analysis services for quantitative assessment of results. Overall, Initio Cell's goal is to enable precision medicine by providing tools and services that can help reduce R&D costs and improve the accuracy of drug discovery and diagnostics.

Classical drug discovery uses 2D cell culture coupled with animal testing for preclinical studies. Neither 2D cell culture nor animal testing truly recapitulate the in vivo micro environments of cells in a human body. The paradigm shift is to use 3D cell culture in lab-on-a- chip devices that can faithfully mimic the in vivo conditions. With this modern drug discovery approach, costs can be reduced ten-fold, results can be achieved ten times faster, animal testing can be significantly reduced and personalized medicine can be realized.

Yet, current solutions have problems. At INITIO, we develop patented/patent-pending multi-functional lab-on-a-chip products and assays aimed at drug discovery. Thanks to our lab-on-a-chip products with innovative designs, different types of assays can simultaneously be performed using a single lab-on-a-chip product. Our products also deliver unique assays that no other lab-on-a-chip product on the market can.

We develop lab-on-a-chip products and assays for 3D Cell Culture. We focus on gradients and cell-to-cell interactions.

Invasion-Chemotaxis chip: a Lab-on-chip for invasion and chemotaxis in vitro assays, that can be visualized under microscope.

Distance-Dependent chip: a Lab-on-chip to study cell-cell interaction, depending on their spatial distance. The chip can be imaged under microscope.